Heterologous production of the lantibiotic Ala(0)actagardine in Escherichia coli.
نویسندگان
چکیده
We report the heterologous production of Ala(0)actagardine in E. coli by co-expression of the substrate peptide GarA and its modification enzymes GarM and GarO. The activity of GarO, a luciferase-like monooxygenase that introduces the unique sulfoxide group of actagardine, was also investigated in vitro.
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عنوان ژورنال:
- Chemical communications
دوره 48 89 شماره
صفحات -
تاریخ انتشار 2012